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Toward unsupervised single-shot diffractive imaging of heterogeneous particles using X-ray free-electron lasers
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2013 (English)In: Optics Express, ISSN 1094-4087, Vol. 21, no 23, 28729-28742 p.Article in journal (Refereed) Published
Abstract [en]

Single shot diffraction imaging experiments via X-ray free-electron lasers can generate as many as hundreds of thousands of diffraction patterns of scattering objects. Recovering the real space contrast of a scattering object from these patterns currently requires a reconstruction process with user guidance in a number of steps, introducing severe bottlenecks in data processing. We present a series of measures that replace user guidance with algorithms that reconstruct contrasts in an unsupervised fashion. We demonstrate the feasibility of automating the reconstruction process by generating hundreds of contrasts obtained from soot particle diffraction experiments.

Place, publisher, year, edition, pages
2013. Vol. 21, no 23, 28729-28742 p.
National Category
Natural Sciences
URN: urn:nbn:se:uu:diva-213926DOI: 10.1364/OE.21.028729ISI: 000327494000115OAI: oai:DiVA.org:uu-213926DiVA: diva2:683635
Available from: 2014-01-05 Created: 2014-01-05 Last updated: 2014-09-26Bibliographically approved

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Maia, Filipe R. N. C.Ekeberg, TomasHantke, Max Felix
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Molecular biophysics
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