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Saccharomyces kluyveri as a model organism to study pyrimidine degradation
Karolinska Institutet. (Molecular Structural Biology)
2008 (English)In: FEMS yeast research (Print), ISSN 1567-1356, E-ISSN 1567-1364, Vol. 8, no 8, 1209-1213 p.Article, review/survey (Refereed) Published
Abstract [en]

The yeast Saccharomyces kluyveri (Lachancea kluyveri), a far relative of Saccharomyces cerevisiae, is not a widely studied organism in the laboratory. However, significant contributions to the understanding of nucleic acid precursors degradation in eukaryotes have been made using this model organism. Here we review eukaryotic pyrimidine degradation with emphasis on the contributions made with S. kluyveri and how this increases our understanding of human disease. Additionally, we discuss the possibilities and limitations of this nonconventional yeast as a laboratory organism.

Place, publisher, year, edition, pages
2008. Vol. 8, no 8, 1209-1213 p.
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Biochemistry and Molecular Biology
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URN: urn:nbn:se:uu:diva-214422DOI: 10.1111/j.1567-1364.2008.00442.xPubMedID: 18823354OAI: oai:DiVA.org:uu-214422DiVA: diva2:685001
Available from: 2014-01-08 Created: 2014-01-08 Last updated: 2017-12-06Bibliographically approved

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Dobritzsch, Doreen

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