Number of MHC alleles is related to parasite loads in natural populations of yellow necked mice, Apodemus flavicollis
2009 (English)In: Evolutionary Ecology Research, ISSN 1522-0613, Vol. 11, no 7, 1085-1097 p.Article in journal (Refereed) Published
Hypothesis: Low levels of immune gene variation (major histocompatibility complex) in it Population arc associated with increased parasite load and infection Intensity. Organism: Different Populations of the yellow necked mouse (Apodemus flavicollis). a common rodent in European deciduous and mixed forest habitats Methods: We assessed genetic diversity at selectively neutral, non-coding markers (microsatellites) and adaptive genetic variation at a functionally important part of the immune complex MHC (major histocompatibility complex). We investigated the load with gastrointestinal parasites non-invasively by faecal egg counts and assessed the influence of population genetic variation on parasite burden Results: Both neutral and adaptive genetic diversity differed between mice populations. We could not detect an effect of neutral genetic diversity on the parasite burden in a population Heterozygosity at the MFIC did not reveal an effect on the parasite burden either. However, we did identify significant effects of the number of different MHC alleles in a population oil parasite burden Mice populations with a large number of different MHC alleles displayed lower parasite loads than those populations with few different MHC alleles
Place, publisher, year, edition, pages
2009. Vol. 11, no 7, 1085-1097 p.
IdentifiersURN: urn:nbn:se:uu:diva-215493ISI: 000271540500007OAI: oai:DiVA.org:uu-215493DiVA: diva2:687466