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An NMR conformational study of the complexes of C-13/H-2 double-labelled 2 '-deoxynucleosides and deoxycytidine kinase (dCK)
Uppsala University, Teknisk-naturvetenskapliga vetenskapsområdet, Faculty of Science and Technology, Biology, Department of Bioorganic Chemistry.
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2000 (English)In: JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 2, ISSN 1470-1820, no 11, 2199-2207 p.Article in journal (Refereed) Published
Abstract [en]

The structures of the bound C-13/H-2 double-labelled [(2' R/S,5' R/S)-H-2(2)-1',2',3',4',5'-C-13(5)]-2'-deoxyadenosine (dAdo) and the corresponding 2'-deoxycytidine (dCyd) moieties in the complexes with human recombinant deoxycytidine kinase (dCK) have be

Place, publisher, year, edition, pages
ROYAL SOC CHEMISTRY , 2000. no 11, 2199-2207 p.
Keyword [en]
CROSS-CORRELATED RELAXATION; TRANSFER-RNA-SYNTHETASE; THYMIDINE KINASE; SUGAR PUCKER; SPECTROSCOPY; BINDING; ENZYME; NOE; 2'-DEOXYADENOSINE; DNA
Identifiers
URN: urn:nbn:se:uu:diva-42163OAI: oai:DiVA.org:uu-42163DiVA: diva2:70064
Note
Addresses: Chattopadhayaya J, Univ Uppsala, Ctr Biomed, Dept Bioorgan Chem, Box 581, S-75123 Uppsala, Sweden Univ Uppsala, Ctr Biomed, Dept Bioorgan Chem, S-75123 Uppsala, Sweden Swedish Univ Agr Sci, Dept Vet Med Chem, S-75123 Uppsala, Sweden Adam MickieAvailable from: 2008-10-17 Created: 2008-10-17 Last updated: 2011-01-14

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