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Genome sequencing and population genomics in non-model organisms
Uppsala University, Disciplinary Domain of Science and Technology, Biology, Department of Ecology and Genetics, Evolutionary Biology.
2014 (English)In: Trends in Ecology & Evolution, ISSN 0169-5347, E-ISSN 1872-8383, Vol. 29, no 1, 51-63 p.Article, review/survey (Refereed) Published
Abstract [en]

High-throughput sequencing technologies are revolutionizing the life sciences. The past 12 months have seen a burst of genome sequences from non-model organisms, in each case representing a fundamental source of data of significant importance to biological research. This has bearing on several aspects of evolutionary biology, and we are now beginning to see patterns emerging from these studies. These include significant heterogeneity in the rate of recombination that affects adaptive evolution and base composition, the role of population size in adaptive evolution, and the importance of expansion of gene families in lineage-specific adaptation. Moreover, resequencing of population samples (population genomics) has enabled the identification of the genetic basis of critical phenotypes and cast light on the landscape of genomic divergence during speciation.

Place, publisher, year, edition, pages
2014. Vol. 29, no 1, 51-63 p.
Keyword [en]
ecological genomics, evolutionary genomics, genome sequencing, molecular evolution, adaptive evolution, positive selection, population genomics, speciation genetics
National Category
Natural Sciences
URN: urn:nbn:se:uu:diva-219411DOI: 10.1016/j.tree.2013.09.008ISI: 000330148000008OAI: oai:DiVA.org:uu-219411DiVA: diva2:703448
Available from: 2014-03-06 Created: 2014-02-28 Last updated: 2014-03-06Bibliographically approved

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Ellegren, Hans
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