Method for immobilization of liposomes in capillary electrophoresis by electrostatic interaction with derivatized agarose
2002 (English)In: Electrophoresis, ISSN 3381-3384, Vol. 23, 3381-3384 p.Article in journal (Refereed) Published
A novel procedure for immobilization of liposomes inside fused-silica capillaries is
demonstrated. First, the inner wall of the capillaries was coated with a positively
charged polymer, composed of derivatized agarose. Subsequently, negatively charged
liposomes were immobilized by electrostatic interaction on the polymer coating. The
developed liposome coated capillaries were used as a nanoseparation tool for studying
interactions between small drug compounds and liposomes. Part of this work was
presented at the 15th International Symposium on Microscale Separations and Analysis,
HPCE 2002, Stockholm, Sweden, April 2002.
Place, publisher, year, edition, pages
2002. Vol. 23, 3381-3384 p.
Capillary electrophoresis; derivatized agarose; electrostatic interaction; immobilized liposomes
IdentifiersURN: urn:nbn:se:uu:diva-42450OAI: oai:DiVA.org:uu-42450DiVA: diva2:70352