uu.seUppsala University Publications
Change search
ReferencesLink to record
Permanent link

Direct link
Reliability of computed tomography measurements in assessment of thigh muscle cross-sectional area and attenuation
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Radiology, Oncology and Radiation Science, Radiology. Department of Radiology, Karolinska University Hospital, Karolinska Institutet, Stockholm, Sweden .
2010 (English)In: BMC Medical Imaging, ISSN 1471-2342, Vol. 10, 18- p.Article in journal (Refereed) Published
Abstract [en]

BACKGROUND: Advancement in technology of computer tomography (CT) and introduction of new medical imaging softwares enables easy and rapid assessment of muscle cross-sectional area (CSA) and attenuation. Before using these techniques in clinical studies there is a need for evaluation of the reliability of the measurements. The purpose of the study was to evaluate the inter- and intra-observer reliability of ImageJ in measuring thigh muscles CSA and attenuation in patients with anterior cruciate ligament (ACL) injury by computer tomography.

METHODS: 31 patients from an ongoing study of rehabilitation and muscle atrophy after ACL reconstruction were included in the study. Axial CT images with slice thickness of 10 mm at the level of 150 mm above the knee joint were analyzed by two investigators independently at two times with a minimum of 3 weeks between the two readings using NIH ImageJ. CSA and the mean attenuation of individual thigh muscles were analyzed for both legs.

RESULTS: Mean CSA and mean attenuation values were in good agreement both when comparing the two observers and the two replicates. The inter- and intraclass correlation (ICC) was generally very high with values from 0.98 to 1.00 for all comparisons except for the area of semimembranosus. All the ICC values were significant (p < 0,001). Pearson correlation coefficients were also generally very high with values from 0.98 to 1.00 for all comparisons except for the area of semimembranosus (0.95 for intraobserver and 0.92 for interobserver).

CONCLUSION: This study has presented ImageJ as a method to monitor and evaluate CSA and attenuation of different muscles in the thigh using CT-imaging. The method shows an overall excellent reliability with respect to both observer and replicate.

Place, publisher, year, edition, pages
2010. Vol. 10, 18- p.
National Category
Medical and Health Sciences
URN: urn:nbn:se:uu:diva-220132DOI: 10.1186/1471-2342-10-18PubMedID: 20701775OAI: oai:DiVA.org:uu-220132DiVA: diva2:704160
Available from: 2014-03-11 Created: 2014-03-11 Last updated: 2015-03-26Bibliographically approved

Open Access in DiVA

No full text

Other links

Publisher's full textPubMed

Search in DiVA

By author/editor
Shalabi, Adel
By organisation
In the same journal
BMC Medical Imaging
Medical and Health Sciences

Search outside of DiVA

GoogleGoogle Scholar
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

Altmetric score

Total: 135 hits
ReferencesLink to record
Permanent link

Direct link