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Dynamic Hysteresis Behaviour of Respiratory System Mechanics
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Anaesthesiology and Intensive Care.
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Anaesthesiology and Intensive Care.
2013 (English)In: Biomedizinische Technik (Berlin. Zeitschrift), ISSN 1862-278X, E-ISSN 0013-5585, Vol. 58Article in journal (Refereed) Published
Abstract [en]

The static pressure-volume (PV) curve of the respiratory system is characterized by hysteresis behaviour. Determination of separate inspiratory and expiratory compliance is required to analyse this phenomenon during the dynamic situation of mechanical ventilation. In five piglets expiratory flow was linearized (flow-controlled expiration, FLEX) to allow for compliance estimation separately for inspiration and expiration. Expiratory compliance was higher than inspiratory compliance along the entire intratidal course, converging at higher volumes. At higher PEEP levels expiratory and inspiratory compliance tended to run more in parallel. We conclude that the analysis of the separate inspiratory and expiratory compliance profiles allows for indicating unfavourable mechanical ventilation settings.

Place, publisher, year, edition, pages
2013. Vol. 58
Keyword [en]
Expiratory peak flow, flow-controlled expiration, mechanical ventilation, respiratory system compliance
National Category
Medical and Health Sciences
Identifiers
URN: urn:nbn:se:uu:diva-219881DOI: 10.1515/bmt-2013-4119ISI: 000329463600119OAI: oai:DiVA.org:uu-219881DiVA: diva2:704406
Conference
Tri-State Conference of the German-Swiss-and-Austrian-Society-for-Biomedical-Technology (BMT), 2013, Graz, AUSTRIA
Available from: 2014-03-12 Created: 2014-03-06 Last updated: 2017-12-05Bibliographically approved

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Vimlati, LaszloLichtwarck-Aschoff, Michael

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