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The shape of intratidal resistance-volume and compliance-volume curves in mechanical ventilation - an animal study
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Anaesthesiology and Intensive Care.
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2013 (English)In: Biomedizinische Technik (Berlin. Zeitschrift), ISSN 0013-5585, Vol. 58Article in journal (Refereed) Published
Abstract [en]

In respiratory system mechanics, the shape of the intratidal pulmonary compliance-volume curve can be used to detect atelectasis or overdistension in the mechanically ventilated lung and thus to optimise the ventilator setting in terms of positive end-expiratory pressure (PEEP) and tidal volume (V-T). To this end, a set of shape-categories had been suggested. Furthermore, a characteristic behaviour of the intratidal resistance is expected as a consequence of alveolar recruitment and overdistension of the airways. We inspect the intratidal compliance and resistance profiles in mechanically ventilated pigs and suggest a classification into slope-categories for the resistance profile which could be used in combination with the compliance shape-categories to optimize PEEP and V-T.

Place, publisher, year, edition, pages
2013. Vol. 58
Keyword [en]
respiratory system mechanics, mechanical ventilation, intratidal resistance, intratidal compliance
National Category
Medical and Health Sciences
URN: urn:nbn:se:uu:diva-219880DOI: 10.1515/bmt-2013-4118ISI: 000329463600118OAI: oai:DiVA.org:uu-219880DiVA: diva2:704409
Tri-State Conference of the German-Swiss-and-Austrian-Society-for-Biomedical-Technology (BMT), 2013, Graz, AUSTRIA
Available from: 2014-03-12 Created: 2014-03-06 Last updated: 2014-03-12Bibliographically approved

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Lichtwarck-Aschoff, Michael
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Anaesthesiology and Intensive Care
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