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Imaging of pain-associated processes in peripheral tissues
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Public Health and Caring Sciences, Family Medicine and Preventive Medicine.
2014 (English)In: Diagnostic Imaging Europe, Vol. 30, no 2, 14-16 p.Article in journal (Other academic) Published
Abstract [en]

Despite the significant effect chronic soft tissue pain such as tennis elbowcan have on the sufferer, the basic pathophysiologic mechanisms underlyingsuch pain are only very poorly understood. In addition, there are currently nosatisfactory methods for the precise localization of pain in peripheral tissues.This article describes the basic biochemistry of the Substance P -Neurokinin 1 (NK1) receptor system and summarizes the findings of arecent study using a PET radioligand specific for the NK1 receptor to identifychronic pain.The results show the potential of the approach, which should be confirmedby larger confirmatory studies.

Place, publisher, year, edition, pages
2014. Vol. 30, no 2, 14-16 p.
National Category
Family Medicine
URN: urn:nbn:se:uu:diva-220718OAI: oai:DiVA.org:uu-220718DiVA: diva2:706300
Available from: 2014-03-19 Created: 2014-03-19 Last updated: 2014-11-12Bibliographically approved

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