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Number of Daily Doses Does Not Affect Compliance with Flucloxacillin Prescriptions
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Pharmacy, Department of Pharmacy.
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Pharmacy, Department of Pharmacy.
2013 (English)In: International Journal of Clinical Medicine, ISSN 2158-284X, E-ISSN 2158-2882, Vol. 4, no 9, 384-387 p.Article in journal (Refereed) Published
Abstract [en]

Objective:

To achieve optimal effect with beta-lactam antibiotics, regimens with frequent dosages have been found nec- essary. However, if compliance is negatively influenced by more frequent dosages, this might hamper the effect of the treatments. Therefore, we have studied whether the numbers of daily dosages influence the compliance with prescribed flucloxacillin regimens.

Design:

A prospective interview study of patients with different dosing regimens of flucloxacil- lin.

Setting:

In the study, 200 patients with different dosing regimens of flucloxacillin underwent structured telephone interviews in order to reveal their compliance with the medication. Of these, 13 were prescribed twice-daily doses, 163 three times daily and 24 patients four times daily regimens.

Results:

There were no statistically significant differences between missed doses and prescribed numbers of daily doses. There was, however, a significant difference in the num- ber of daily doses and experiences associated with the medication.

Conclusions:

This study shows that patients comply well with regimens of up to four daily doses of flucloxacillin, despite experiencing increasing difficulties with regimens of more frequent dosages.

Place, publisher, year, edition, pages
2013. Vol. 4, no 9, 384-387 p.
National Category
Basic Medicine
Identifiers
URN: urn:nbn:se:uu:diva-223924DOI: 10.4236/ijcm.2013.49069OAI: oai:DiVA.org:uu-223924DiVA: diva2:714465
Available from: 2014-04-28 Created: 2014-04-28 Last updated: 2017-12-05Bibliographically approved

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