uu.seUppsala University Publications
Change search
ReferencesLink to record
Permanent link

Direct link
Analysis of the Wnt gene repertoire in an onychophoran provides new insights into the evolution of segmentation
Uppsala University, Disciplinary Domain of Science and Technology, Earth Sciences, Department of Earth Sciences, Palaeobiology.
Uppsala University, Disciplinary Domain of Science and Technology, Earth Sciences, Department of Earth Sciences, Palaeobiology.
Show others and affiliations
2014 (English)In: EvoDevo, ISSN 2041-9139, Vol. 5, 14- p.Article in journal (Refereed) Published
Abstract [en]

Background: The Onychophora are a probable sister group to Arthropoda, one of the most intensively studied animal phyla from a developmental perspective. Pioneering work on the fruit fly Drosophila melanogaster and subsequent investigation of other arthropods has revealed important roles for Wnt genes during many developmental processes in these animals. Results: We screened the embryonic transcriptome of the onychophoran Euperipatoides kanangrensis and found that at least 11 Wnt genes are expressed during embryogenesis. These genes represent 11 of the 13 known subfamilies of Wnt genes. Conclusions: Many onychophoran Wnt genes are expressed in segment polarity gene-like patterns, suggesting a general role for these ligands during segment regionalization, as has been described in arthropods. During early stages of development, Wnt2, Wnt4, and Wnt5 are expressed in broad multiple segment-wide domains that are reminiscent of arthropod gap and Hox gene expression patterns, which suggests an early instructive role for Wnt genes during E. kanangrensis segmentation.

Place, publisher, year, edition, pages
2014. Vol. 5, 14- p.
Keyword [en]
Development, Evolution, Segmentation, Segment polarity, Wnt signalling
National Category
Natural Sciences
URN: urn:nbn:se:uu:diva-224742DOI: 10.1186/2041-9139-5-14ISI: 000334643600001OAI: oai:DiVA.org:uu-224742DiVA: diva2:718329
Available from: 2014-05-20 Created: 2014-05-19 Last updated: 2014-05-20Bibliographically approved

Open Access in DiVA

fulltext(3833 kB)30 downloads
File information
File name FULLTEXT01.pdfFile size 3833 kBChecksum SHA-512
Type fulltextMimetype application/pdf

Other links

Publisher's full text

Search in DiVA

By author/editor
Hogvall, MattiasBudd, Graham E.Janssen, Ralf
By organisation
In the same journal
Natural Sciences

Search outside of DiVA

GoogleGoogle Scholar
Total: 30 downloads
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

Altmetric score

Total: 224 hits
ReferencesLink to record
Permanent link

Direct link