Idenitification of the active site of poly(A)-specific ribonuclease by site-directed mutagensis and Fe2+-mediated cleavage.
2002 (English)In: . J. Biol. Chem., Vol. 277, 5982-5987 p.Article in journal (Refereed) Published
Poly(A)-specific ribonuclease (PARN) is the only so far
characterized mammalian exoribonuclease with high specificity
for degrading the mRNA poly(A) tail. PARN belongs to the RNase
D family of nucleases, a family characterized by the presence of
Place, publisher, year, edition, pages
2002. Vol. 277, 5982-5987 p.
IdentifiersURN: urn:nbn:se:uu:diva-44967OAI: oai:DiVA.org:uu-44967DiVA: diva2:72874