Quality of Life in men with abdominal aortic aneurysm
Independent thesis Advanced level (degree of Master (One Year)), 20 credits / 30 HE creditsStudent thesisAlternative title
Quality of Life in men with abdominal aortic aneurysm (English)
Objective: The objective of this study was to investigate if there’s a difference in health related QoL between men with an abdominal aortic aneurysm (AAA) and men with a normal aorta, after screening and at 1 year follow-up.
Methods: Within an ongoing prospective population-based case-control study (UpAAA) a total of 197 men with screening detected AAA (≥25 mm) and 48 age matched control subjects with a normal aorta (≤24 mm) completed the QoL-questionnaires EQ-5D and SF-36 after screening and after 1 year.
Results: Between group comparisons at baseline, men with AAA reported lower Physical Function and General Health in SF-36 while the control-group reported more Bodily Pain in both EQ-5D and SF-36. At 1 year follow-up the AAA-group still reported lower Physical Function and the control-group more Bodily Pain. Within group comparisons from EQ-5D showed a lower function in Mobility, Usual activities and Health state in the AAA-group. In SF-36 the AAA-group had a total lower Physical Component Summary (PCS). Men with normal aorta had more problems with Pain/Discomfort, Anxiety/Depression and lower Health state which was also observed in SF-36 where they had scored significant lower in both Physical Component Summary (PCS) and Mental Component Summary (MCS) at 1 year follow-up.
Conclusion: The result from this study indicates no negative effect in health related QoL in men with AAA after screening or after 1 year. The lower means reported in General Health and Physical Function could be explained by the comorbidity in the AAA-group. However, none of the results from the SF-36 scales showed a mean-value under the norms for the age-matched Swedish population. Further research in this area is needed, and a disease-specific health-related quality of life questionnaire may be necessary.
Place, publisher, year, edition, pages
2014. , 26 p.
Abdominal aortic aneurysm, screening, quality of life
IdentifiersURN: urn:nbn:se:uu:diva-227655OAI: oai:DiVA.org:uu-227655DiVA: diva2:730753
Subject / course