Quantification of Colocalisation; Co-Occurrence, Correlation, Empty Voxels, Regions of Interest and Thresholding
2014 (English)In: Biophysical Journal, ISSN 0006-3495, E-ISSN 1542-0086, Vol. 106, no 2, 602A-602A p.Article in journal, Meeting abstract (Other academic) Published
Measuring colocalisation is not straightforward with a plethora of coefficients that encapsulate different definitions. Measurements may also be implemented differently. Not only do measurements differ; interconversion is impossible making comparisons challenging. There is a need to cull coefficients and for clear definitions of what precisely is meant by colocalisation in individual studies. Colocalisation can be considered to have two components; co-occurrence which reports whether the fluorophores are found together and correlation which reports on the similarity in their patterns of intensity.
Place, publisher, year, edition, pages
2014. Vol. 106, no 2, 602A-602A p.
IdentifiersURN: urn:nbn:se:uu:diva-228605DOI: 10.1016/j.bpj.2013.11.3333ISI: 000337000403385OAI: oai:DiVA.org:uu-228605DiVA: diva2:734557
58th Annual Meeting of the Biophysical-Society, FEB 15-19, 2014, San Francisco, CA