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Technical requirements for Na¹⁸F PET bone imaging of patients being treated using a Taylor spatial frame
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Radiology, Oncology and Radiation Science, Radiology. Department of Molecular Medicine and Surgery, Karolinska Institute, Stockholm, Sweden.
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2014 (English)In: Journal of Nuclear Medicine Technology, ISSN 0091-4916, Vol. 42, no 1, 33-36 p.Article in journal (Refereed) Published
Abstract [en]

Diagnosis of new bone growth in patients with compound tibia fractures or deformities treated using a Taylor spatial frame is difficult with conventional radiography because the frame obstructs the images and creates artifacts. The use of Na18F PET studies may help to eliminate this difficulty.


Patients were positioned on the pallet of a clinical PET/CT scanner and made as comfortable as possible with their legs immobilized. One bed position covering the site of the fracture, including the Taylor spatial frame, was chosen for the study. A topogram was performed, as well as diagnostic and attenuation correction CT. The patients were given 2 MBq of Na18F per kilogram of body weight. A 45-min list-mode acquisition was performed starting at the time of injection, followed by a 5-min static acquisition 60 min after injection. The patients were examined 6 wk after the Taylor spatial frame had been applied and again at 3 mo to assess new bone growth.


A list-mode reconstruction sequence of 1 × 1,800 and 1 × 2,700 s, as well as the 5-min static scan, allowed visualization of regional bone turnover.


With Na18F PET/CT, it was possible to confirm regional bone turnover as a means of visualizing bone remodeling without the interference of artifacts from the Taylor spatial frame. Furthermore, dynamic list-mode acquisition allowed different sequences to be performed, enabling, for example, visualization of tracer transport from blood to the fracture site.

Place, publisher, year, edition, pages
2014. Vol. 42, no 1, 33-36 p.
National Category
Radiology, Nuclear Medicine and Medical Imaging
URN: urn:nbn:se:uu:diva-231431DOI: 10.2967/jnmt.113.133082PubMedID: 24436472OAI: oai:DiVA.org:uu-231431DiVA: diva2:744565
Available from: 2014-09-08 Created: 2014-09-08 Last updated: 2015-03-25Bibliographically approved

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