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Diffusion tensor fiber tractography of the olfactory tract
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Radiology, Oncology and Radiation Science, Radiology. Department of Molecular Medicine and Surgery, Karolinska Institute, Stockholm, Sweden.
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2011 (English)In: Magnetic Resonance Imaging, ISSN 0730-725X, E-ISSN 1873-5894, Vol. 29, no 2, 289-292 p.Article in journal (Refereed) Published
Abstract [en]

Magnetic resonance diffusion tensor imaging with fiber tracking is used for 3-dimensional visualization of the nervous system. Peripheral nerves and all cranial nerves, except for the olfactory tract, have previously been visualized. The olfactory tracts are difficult to depict with diffusion-weighted imaging due to the high sensitivity to susceptibility artifacts at the base of the skull. Here we report an optimized single-shot diffusion-weighted echo planar imaging sequence that can visualize the olfactory tracts with fiber tracking. Five healthy individuals were examined, and the olfactory tracts could be fiber tracked with the diffusion-weighted sequence. For comparison and as a negative control, an anosmic patient was examined. No olfactory tracts were visualized on T2-weighted nor diffusion-weighted fiber tracking images. Measuring diffusion in the olfactory tracts promise to facilitate the identification of different hyposmic and anosmic conditions.

Place, publisher, year, edition, pages
2011. Vol. 29, no 2, 289-292 p.
National Category
Clinical Medicine
URN: urn:nbn:se:uu:diva-231544DOI: 10.1016/j.mri.2010.07.004PubMedID: 20850236OAI: oai:DiVA.org:uu-231544DiVA: diva2:744894
Available from: 2014-09-09 Created: 2014-09-09 Last updated: 2015-03-25Bibliographically approved

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