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Unexpected cure from cutaneous leukocytoclastic vasculitis in a patient treated with N-butyldeoxynojirimycin (miglustat) for Gaucher disease
Department of Clinical Pathology and Cytology, Karolinska University Hospital Huddinge, Stockholm, Sweden.
2012 (English)In: Advances in Medical Sciences, ISSN 1896-1126, E-ISSN 1898-4002, Vol. 57, no 1, 169-173 p.Article in journal (Refereed) Published
Abstract [en]

Cutaneous leukocytoclastic vasculitis (CLV) is a necrotizing inflammation of the small vessels in the dermis. We report the case of a Swedish man with an untreated N370S/L444P Gaucher disease who developed CLV at the age of 79 years. The patient has been treated for CLV with topical and oral corticosteroids, moisturizing agents, and periodically with antibiotics for 3 years without improvement. Administration of miglustat (N-butyldeoxynojirimycin; Zavesca®) because of progress of Gaucher disease resulted in a prompt and durable cure of the CLV.

Place, publisher, year, edition, pages
2012. Vol. 57, no 1, 169-173 p.
National Category
Clinical Medicine
Identifiers
URN: urn:nbn:se:uu:diva-233799DOI: 10.2478/v10039-012-0021-yPubMedID: 22515974OAI: oai:DiVA.org:uu-233799DiVA: diva2:754338
Available from: 2014-10-10 Created: 2014-10-10 Last updated: 2017-12-05Bibliographically approved

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