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Study of proteins related to the thyroid in the endometrium of women with unexplained infertilityTherese Borén
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Women's and Children's Health.
2014 (English)Independent thesis Basic level (university diploma), 10 credits / 15 HE creditsStudent thesis
Abstract [en]

Infertility is a global health issue that can have many causes. It is, however, not always known why some couples cannot conceive even though there are no apparent reason in either the man or the woman. The woman can have normal menstrual cycles and the man can have normal semen.The purpose of this study was to investigate the presence and distribution of thyroid related proteins in endometrial biopsies. Eight biopsies was taken from women with unexplained infertility and 35 biopsies from healthy fertile woman. These were divided into smaller groups based on menstrual cycle day and analysed with immunohistochemistry for the detection of the thyroid related proteins MCT8 and DIO2.There were no significant differences between the groups and therefore are more studies required in the subject to be able to find factors that may help solving some cases of unexplainedinfertility.

Place, publisher, year, edition, pages
2014. , 18 p.
Keyword [en]
MCT8, DIO2, immunohistochemistry, menstrual cycle, ovulatory cycle
National Category
Biomedical Laboratory Science/Technology
URN: urn:nbn:se:uu:diva-234692OAI: oai:DiVA.org:uu-234692DiVA: diva2:757571
Educational program
Biomedical Laboratory Science Programme
Available from: 2014-10-22 Created: 2014-10-22 Last updated: 2014-10-22Bibliographically approved

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