uu.seUppsala University Publications
Change search
ReferencesLink to record
Permanent link

Direct link
Temporomandibular condylar alterations in juvenile idiopathic arthritis most common in longitudinally severe disease despite medical treatment
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Oral and Maxillofacial Surgery.
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Women's and Children's Health, Pediatrics.
Show others and affiliations
2014 (English)In: Pediatric Rheumatology, ISSN 1546-0096, Vol. 12, 43- p.Article in journal (Refereed) Published
Abstract [en]

Background: Juvenile idiopathic arthritis (JIA) is an autoimmune, heterogeneous disease and the temporomandibular joint (TMJ) can be affected, with consequences for mandibular growth and function. The aim of this study was to evaluate the importance of longitudinal medical treatment and the burden of disease activity on the development of temporomandibular condylar alterations as judged on panoramic radiographs. Methods: The study was a retrospective evaluation of dental and medical records in consecutive JIA patients referred to three specialist dental clinics in Sweden during an eight-year period. Data on the total pharmacological treatment and disease activity were evaluated longitudinally from disease onset to the time of the panoramic examination, during a median observation period of 2.5 years. The radiographs were analysed in terms of structural and shape alterations in the condyles and judged dichotomously. Results: Panoramic examinations were analysed in 158 patients from 266 referrals diagnosed with JIA. Condylar alterations (shape or structural) were seen in 68 patients (43%). Patients with condylar alterations were more extensively treated over time compared with those without condylar alterations. Powerful disease activity and/or potent medication at any time during the course of the disease implied an increased risk of alterations. Conclusions: Patients with JIA who require more intensive medication over time run the greatest risk of condylar alterations. As yet, current medical programmes have not been specified for the TMJ and more knowledge in this area is needed.

Place, publisher, year, edition, pages
2014. Vol. 12, 43- p.
Keyword [en]
Adolescent, Arthritis juvenile rheumatoid/diagnoses, Child, Retrospective studies, Temporomandibular joint
National Category
Rheumatology and Autoimmunity Pediatrics
URN: urn:nbn:se:uu:diva-235330DOI: 10.1186/1546-0096-12-43ISI: 000342382200001OAI: oai:DiVA.org:uu-235330DiVA: diva2:760930
Available from: 2014-11-05 Created: 2014-10-30 Last updated: 2014-11-05Bibliographically approved

Open Access in DiVA

fulltext(356 kB)64 downloads
File information
File name FULLTEXT01.pdfFile size 356 kBChecksum SHA-512
Type fulltextMimetype application/pdf

Other links

Publisher's full text

Search in DiVA

By author/editor
Berntson, Lillemor
By organisation
Oral and Maxillofacial SurgeryPediatrics
In the same journal
Pediatric Rheumatology
Rheumatology and AutoimmunityPediatrics

Search outside of DiVA

GoogleGoogle Scholar
Total: 64 downloads
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

Altmetric score

Total: 326 hits
ReferencesLink to record
Permanent link

Direct link