uu.seUppsala University Publications
Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
A Contact Angle Study of the Interaction between Embedded Amphiphilic Molecules and the PDMS Matrix in an Aqueous Environment
Uppsala University, Disciplinary Domain of Science and Technology, Technology, Department of Engineering Sciences, Microsystems Technology.
Uppsala University, Disciplinary Domain of Science and Technology, Technology, Department of Engineering Sciences, Microsystems Technology.
Uppsala University, Disciplinary Domain of Science and Technology, Technology, Department of Engineering Sciences, Microsystems Technology.
Show others and affiliations
2014 (English)In: Micromachines, ISSN 2072-666X, E-ISSN 2072-666X, Vol. 5, no 3, 515-527 p.Article in journal (Refereed) Published
Abstract [en]

Poly(dimethylsiloxane) (PDMS) surface modification via gradient-induced transport of embedded amphiphilic molecules is a novel, easy, flexible, and environmentally friendly approach for reducing protein adsorption on PDMS in microfluidic applications. To better understand the processing and the potential use in the viability-sensitive applications such as manipulation and culturing of primary neural cells, we systematically investigate how embedded molecules interact with a PDMS matrix and its surface in aqueous environments by studying the wetting angle over time under various processing conditions, including water exposure time, water exposure temperature, curing master materials, in addition to comparing different embedded amphiphilic molecules. The results indicate that the water exposure time clearly plays an important role in the surface properties. Our interpretation is that molecular rearrangement of the surface-embedded molecules improves surface coverage in the short term; while over a longer period, the transport of molecules embedded in the bulk enhance its coverage. However, this improvement finally terminates when molecules transported from the bulk to the surface are not sufficient to replace the molecules leaching into the water.

Place, publisher, year, edition, pages
2014. Vol. 5, no 3, 515-527 p.
Keyword [en]
gradient-induced transport, PDMS surface modification, embedded amphiphilic molecules
National Category
Electrical Engineering, Electronic Engineering, Information Engineering
Identifiers
URN: urn:nbn:se:uu:diva-237586DOI: 10.3390/mi5030515ISI: 000343094500010OAI: oai:DiVA.org:uu-237586DiVA: diva2:768985
Available from: 2014-12-05 Created: 2014-12-03 Last updated: 2017-12-05Bibliographically approved

Open Access in DiVA

fulltext(1753 kB)256 downloads
File information
File name FULLTEXT01.pdfFile size 1753 kBChecksum SHA-512
40a5a2df311afec5b2f1baf4b4485201aec0b9041722f9faedb63da390f832fe64015570b8cd22c8722e9a59d4085b50f008b620f249ec70e3e891c0e13079da
Type fulltextMimetype application/pdf

Other links

Publisher's full text

Authority records BETA

Hjort, KlasWu, Zhigang

Search in DiVA

By author/editor
Hjort, KlasWu, Zhigang
By organisation
Microsystems Technology
In the same journal
Micromachines
Electrical Engineering, Electronic Engineering, Information Engineering

Search outside of DiVA

GoogleGoogle Scholar
Total: 256 downloads
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

doi
urn-nbn

Altmetric score

doi
urn-nbn
Total: 925 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf