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Sexual risk behaviour and donor deferral in Europe
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Immunology, Genetics and Pathology, Clinical Immunology.
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2014 (English)In: Vox Sanguinis, ISSN 0042-9007, E-ISSN 1423-0410, Vol. 107, no 4, 420-427 p.Article in journal (Refereed) Published
Abstract [en]

One of the most controversial policies in blood transfusion worldwide is the permanent deferral from donating blood of men with sexual contacts to other men (MSM). This policy was implemented for safety reasons as sex between men is known to be a high risk factor for acquiring severe infectious diseases transmissible by blood transfusion. Sexual contacts among heterosexual persons may hold similar risks but a clear-cut discrimination between different individual risks is impossible. Nevertheless, the current blood donor deferral periods defined by European Union (EU) legislation depend on a distinction of different grades of risk with respect to sexual behaviour. Under the aegis of the Steering Committee on Blood Transfusion (CD-P-TS) of the Council of Europe (CoE), an international working group evaluated epidemiological and behavioural data, modelling studies on residual risk and spread of infections, and studies on adherence to donor selection criteria. The aim was to distinguish sexual behaviour of different risk categories. It was concluded, that existing data confirm that MSM and commercial sex workers (CSW) are groups at high risk. Any further grading lacks a scientific data base. Modelling studies indicate that adherence to deferral policies is of major relevance suggesting that good donor adherence may outweigh the small negative effects on blood safety postulated for changing from permanent to temporary deferral periods for high risk sexual behaviours. The fact that a considerable percentage of donors are MSM - despite the permanent deferral policy - demonstrates the need to increase donor understanding and adherence.

Place, publisher, year, edition, pages
2014. Vol. 107, no 4, 420-427 p.
Keyword [en]
donors, epidemiology, motivation, recruitment, residual risk estimation, transfusion - transmissible infections
National Category
Immunology in the medical area
URN: urn:nbn:se:uu:diva-238554DOI: 10.1111/vox.12179ISI: 000344227100015PubMedID: 25040600OAI: oai:DiVA.org:uu-238554DiVA: diva2:772916
Available from: 2014-12-17 Created: 2014-12-14 Last updated: 2014-12-17Bibliographically approved

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