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Gastrointestinal Quality-of-Life After Cholecystectomy: Indication Predicts Gastrointestinal Symptoms and Abdominal Pain
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2014 (English)In: World Journal of Surgery, ISSN 0364-2313, E-ISSN 1432-2323, Vol. 38, no 12, 3075-3081 p.Article in journal (Refereed) Published
Abstract [en]

Despite the fact that cholecystectomy is a common surgical procedure, the impact on long-term gastrointestinal quality of life is not fully known. All surgical procedures for gallstone disease performed at Mora County Hospital, Sweden, between 2 January 2002 and 2 January 2005, were registered on a standard database form. In 2007, all patients under the age of 80 years at follow-up were requested to fill in a form containing the Gastrointestinal Quality-of-Life Index (GIQLI) questionnaire and a number of additional questions. The outcome was analysed with respect to age, gender, smoking, surgical technique, and original indication for cholecystectomy. A total of 627 patients (447 women, 180 men) underwent cholecystectomy, including laparoscopic cholecystectomy (N = 524), laparoscopic cholecystectomy converted to open cholecystectomy (N = 43), and open cholecystectomy (N = 60). The mean time between cholecystectomy and follow-up with the questionnaire was 49 months. The participation rate was 79 %. Using multivariate analysis in the form of generalised linear modelling, the original indication for cholecystectomy in combination with gender (p = 0.0042) was found to predict the GIQLI score. Female gender in combination with biliary colic as indication for cholecystectomy correlated with low GIQLI scores. Female gender also correlated with a higher risk for pain in the right upper abdominal quadrant after cholecystectomy (p = 0.028). We found the original indication for cholecystectomy, together with gender, to predict gastrointestinal symptoms and abdominal pain after cholecystectomy. Careful evaluation of symptoms is important before planning elective cholecystectomy.

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2014. Vol. 38, no 12, 3075-3081 p.
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URN: urn:nbn:se:uu:diva-239764DOI: 10.1007/s00268-014-2736-3ISI: 000345103900009PubMedID: 25189441OAI: oai:DiVA.org:uu-239764DiVA: diva2:775278
Available from: 2014-12-31 Created: 2014-12-30 Last updated: 2014-12-31Bibliographically approved

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Karlson, Britt-Marie
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Upper Abdominal Surgery
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