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Single fiber EMG Fiber density and its relationship to Macro EMG amplitude in reinnervation
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Neuroscience, Clinical Neurophysiology.
2014 (English)In: Journal of Electromyography & Kinesiology, ISSN 1050-6411, E-ISSN 1873-5711, Vol. 24, no 6, 941-946 p.Article in journal (Refereed) Published
Abstract [en]

The objective was to elucidate the relation between the Macro EMG parameters fiber density (FD) and Macro amplitude in reinnervation in the purpose to use the FD parameter as a surrogate marker for reinnervation instead of the Macro amplitude. Macro EMG with FD was performed in 278 prior polio patients. The Biceps Brachii and the Tibialis anterior muscles were investigated. FD was more sensitive for detection of signs of reinnervation but showed lesser degree of abnormality than the Macro amplitude. FD and Macro MUP amplitude showed a non-linear relation with a great variation in FD for given Macro amplitude level. The relatively smaller increase in FD compared to Macro amplitude in addition to the non-linear relationship between the FD and the Macro amplitude regarding reinnervation in prior polio can be due to technical reasons and muscle fiber hypertrophy. The FD parameter has a relation to Macro MUP amplitude but cannot alone be used as a quantitative marker of the degree of reinnervation.

Place, publisher, year, edition, pages
2014. Vol. 24, no 6, 941-946 p.
Keyword [en]
Fiber density, EMG, Macro EMG, Polio
National Category
Physiology
Identifiers
URN: urn:nbn:se:uu:diva-239750DOI: 10.1016/j.jelekin.2014.05.010ISI: 000345125000024PubMedID: 24973305OAI: oai:DiVA.org:uu-239750DiVA: diva2:775289
Available from: 2014-12-31 Created: 2014-12-30 Last updated: 2017-12-05Bibliographically approved

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Sandberg, Arne

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