uu.seUppsala University Publications
Change search
ReferencesLink to record
Permanent link

Direct link
Three crocodilian genomes reveal ancestral patterns of evolution among archosaurs
Show others and affiliations
2014 (English)In: Science, ISSN 0036-8075, E-ISSN 1095-9203, Vol. 346, no 6215, 1335-+ p.Article in journal (Refereed) Published
Abstract [en]

To provide context for the diversification of archosaurs-the group that includes crocodilians, dinosaurs, and birds-we generated draft genomes of three crocodilians: Alligator mississippiensis (the American alligator), Crocodylus porosus (the saltwater crocodile), and Gavialis gangeticus (the Indian gharial). We observed an exceptionally slow rate of genome evolution within crocodilians at all levels, including nucleotide substitutions, indels, transposable element content and movement, gene family evolution, and chromosomal synteny. When placed within the context of related taxa including birds and turtles, this suggests that the common ancestor of all of these taxa also exhibited slow genome evolution and that the comparatively rapid evolution is derived in birds. The data also provided the opportunity to analyze heterozygosity in crocodilians, which indicates a likely reduction in population size for all three taxa through the Pleistocene. Finally, these data combined with newly published bird genomes allowed us to reconstruct the partial genome of the common ancestor of archosaurs, thereby providing a tool to investigate the genetic starting material of crocodilians, birds, and dinosaurs.

Place, publisher, year, edition, pages
2014. Vol. 346, no 6215, 1335-+ p.
National Category
Evolutionary Biology
URN: urn:nbn:se:uu:diva-241965DOI: 10.1126/science.1254449ISI: 000346189600040OAI: oai:DiVA.org:uu-241965DiVA: diva2:781978
Available from: 2015-01-19 Created: 2015-01-19 Last updated: 2015-01-19Bibliographically approved

Open Access in DiVA

No full text

Other links

Publisher's full text

Search in DiVA

By author/editor
Suh, AlexanderJarvis, Erich D.
By organisation
Evolutionary Biology
In the same journal
Evolutionary Biology

Search outside of DiVA

GoogleGoogle Scholar
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

Altmetric score

Total: 238 hits
ReferencesLink to record
Permanent link

Direct link