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Levels of dynorphin peptides in the central nervous system and pituitary gland of the spontaneously hypertensive rat
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Pharmacy, Department of Pharmaceutical Biosciences. (Pharmacology)
1997 (English)In: Neurochemistry International, ISSN 0197-0186, E-ISSN 1872-9754, Vol. 31, no 1, 27-32 p.Article in journal (Refereed) Published
Abstract [en]

The levels of dynorphin A-like immunoreactivity (Dyn A-LI) and dynorphin B-like immunoreactivity (Dyn B-LI) were determined in various regions of brain, spinal cord and pituitary gland in spontaneously hypertensive rats (SHRs) as compared with the normotensive Wistar-Kyoto rats (WKYs). SHRs had significantly lower levels of Dyn A-LI and Dyn B-LI in the neurointermediate pituitary lobe and in the hippocampus. Conversely, the levels of Dyn A-LI and Dyn B-LI were higher in the hypothalamus, striatum and periaqueductal gray of the SHRs.

Place, publisher, year, edition, pages
1997. Vol. 31, no 1, 27-32 p.
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Pharmaceutical Sciences Medical and Health Sciences
URN: urn:nbn:se:uu:diva-50727DOI: 10.1016/S0197-0186(96)00137-4ISI: A1997XD21500004PubMedID: 9185161OAI: oai:DiVA.org:uu-50727DiVA: diva2:78636
Available from: 2008-10-17 Created: 2008-10-17 Last updated: 2011-03-10Bibliographically approved

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