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Exercise tests in large groups of children are not a suitable screening procedure for undiagnosed asthma.
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Neuroscience.
1997 (English)In: Allergy. European Journal of Allergy and Clinical Immunology, ISSN 0105-4538, E-ISSN 1398-9995, Vol. 52, no 11, 1128-32 p.Article in journal (Refereed) Published
Abstract [en]

Schoolchildren (n = 473), 12-13 years of age, from five schools, and without known asthma, participated in a screening test for exercise-induced asthma (EIA). The children were tested in large groups of 10-15 pupils. Peak expiratory flow (PEF) was measured before, immediately after, and 6-8 min after 6 min of running exercises in a gymnasium. A fall in PEF of at least 10% on two separate test occasions was considered an abnormal result. Children with abnormal results were given an asthma questionnaire and then tested individually in hospital with a standardized exercise test measuring FEV1, PEF, and flow/volume curve. In the screening test, 23 (4.9%) of the 473 children had an abnormal result. When tested in hospital, five (1%) children had a decrease in PEF and/or FEV1 of at least 10% (10-14%) after exercise. Furthermore, three of these five children had a history indicating mild EIA. We conclude that the use of PEF measurement as a screening method for EIA in large groups of schoolchildren cannot be recommended because it yields many false-positive results.

Place, publisher, year, edition, pages
1997. Vol. 52, no 11, 1128-32 p.
National Category
Medical and Health Sciences
URN: urn:nbn:se:uu:diva-244784PubMedID: 9404568OAI: oai:DiVA.org:uu-244784DiVA: diva2:789845
Available from: 2015-02-20 Created: 2015-02-20 Last updated: 2015-02-20

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