HIV-1 protease inhibitors based on acyclic carbohydrates
1998 (English)In: Journal of Organic Chemistry, ISSN 0022-3263, Vol. 63, no 15, 4898-4906 p.Article in journal (Refereed) Published
A series of acyclic C2-symmetric HIV protease inhibitors readily accessible from D-mannitol have been developed. Several of the compounds synthesized showed significant in vitro activity against HIV-1 protease.
Place, publisher, year, edition, pages
1998. Vol. 63, no 15, 4898-4906 p.
HUMAN-IMMUNODEFICIENCY-VIRUS; BETA-D-GLUCOSE; D-MANNITOL; GLYCIDYL DERIVATIVES; VIRAL INFECTIVITY; AIDS; DRUGS; PEPTIDOMIMETICS; SYMMETRY; DESIGN
Pharmaceutical Sciences Medical Biotechnology (with a focus on Cell Biology (including Stem Cell Biology), Molecular Biology, Microbiology, Biochemistry or Biopharmacy)
IdentifiersURN: urn:nbn:se:uu:diva-51172DOI: 10.1021/jo971562cOAI: oai:DiVA.org:uu-51172DiVA: diva2:79081