uu.seUppsala University Publications
Change search
ReferencesLink to record
Permanent link

Direct link
Quality of life in relation to the traffic pollution indicators NO2 and NOx: results from the Swedish GA(2)LEN survey
Show others and affiliations
2014 (English)In: BMJ open respiratory research, ISSN 2052-4439, Vol. 1, no 1, e000039Article in journal (Refereed) Published
Abstract [en]

BACKGROUND: Asthma is a chronic disease that may affect daily activities and quality of life. Asthmatics have higher incidence of chronic rhinosinusitis (CRS) and asthma is associated with sinonasal inflammation and nasal symptoms, that all impair quality of life. Worsening of asthma has been found associated with levels of nitrogen dioxide as traffic indicator.

AIMS: The aim of the study was to evaluate the impact of traffic pollution indicated by nitrogen oxides (NO2 and NOx) on quality of life in asthmatic persons, individuals with CRS and controls.

METHODS: Within the Swedish Ga(2)len (Global Allergy and Asthma European Network), 605 asthmatics with and without CRS, 110 individuals with CRS only and 226 controls from four cities were surveyed. The mini Asthma Quality of life Questionnaire (mAQLQ) and the Euro Quality of Life (EQ-5D) health questionnaire were used. Air pollution concentrations at the home address were modelled using dispersion models.

RESULTS: Levels of NO2 (geometric mean 10.1 μg/m(3) (95% CI 9.80 to 10.5) and NOx (12.1 μg/m(3), 11.7 to 12.6) were similar among conditions (controls, asthmatics, individuals with CRS and asthmatics with CRS). The mAQLQ overall score was not found associated with levels of NO2 or NOx, with or without adjustments, and neither was scores within each of the four domains of mAQLQ: symptoms, activity limitations, emotional functions and effects of environmental stimuli. The mean EQ-5D index value, based on the five dimensions mobility, self-care, usual activities, pain/discomfort and anxiety depression, was also found unrelated to NO2 and NOx.

CONCLUSIONS: At moderate exposure levels traffic pollution appears not to affect quality of life.

Place, publisher, year, edition, pages
2014. Vol. 1, no 1, e000039
National Category
Respiratory Medicine and Allergy
URN: urn:nbn:se:uu:diva-245743DOI: 10.1136/bmjresp-2014-000039PubMedID: 25478186OAI: oai:DiVA.org:uu-245743DiVA: diva2:791418
Available from: 2015-02-27 Created: 2015-02-27 Last updated: 2015-04-17Bibliographically approved

Open Access in DiVA

No full text

Other links

Publisher's full textPubMed

Search in DiVA

By author/editor
Janson, Christer
By organisation
Respiratory Medicine and Allergology
Respiratory Medicine and Allergy

Search outside of DiVA

GoogleGoogle Scholar
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

Altmetric score

Total: 157 hits
ReferencesLink to record
Permanent link

Direct link