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Analysis of HLA-Class II DQA1, DQB1, DRB1 and DPB1 in Italian Multiple Sclerosis Patients
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Immunology, Genetics and Pathology, Genomics.
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1995 (English)In: European journal of immunogenetics, ISSN 0960-7420, E-ISSN 1365-2370, Vol. 22, no 2, 171-178 p.Article in journal (Refereed) Published
Abstract [en]

We studied the allelic constitution at the HLA class II DQA1, DQB1, DRB1 and DPB1 in 94 Italian multiple sclerosis (MS) patients and 98 controls. No significant increase in the frequency of DR2 alleles was detected among MS patients, as previously observed both in European and some Italian studies. A slight increase was found for the DQA1*0301 and DQB1*0602 alleles in the MS patients. No significant association was found with the glutamine residue at position 34 of the DQ alpha chain, which was noted previously in MS patients from northern Europe.

Place, publisher, year, edition, pages
1995. Vol. 22, no 2, 171-178 p.
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Medical and Health Sciences
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URN: urn:nbn:se:uu:diva-51401PubMedID: 7605774OAI: oai:DiVA.org:uu-51401DiVA: diva2:79310
Available from: 2008-10-17 Created: 2008-10-17 Last updated: 2017-12-04Bibliographically approved

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Allen, MarieGyllensten, Ulf

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