The mitotic checkpoint protein kinase BUB1 is an engine in the TGF-beta signaling apparatus
2015 (English)In: Science Signaling, ISSN 1937-9145, Vol. 8, no 359, fs1Article in journal, Editorial material (Other academic) Published
The transforming growth factor-beta (TGF-beta) pathway mediates critical events in cell behavior that contribute to development and disease. The mitotic checkpoint guarantees faithful chromosomal segregation during cell division. In the 6 January 2015 issue of Science Signaling, Nyati et al. reported that the mitotic checkpoint kinase BUB1 promotes the activity of TGF-beta receptors, which adds new molecular links between these fundamental biological processes.
Place, publisher, year, edition, pages
2015. Vol. 8, no 359, fs1
Biochemistry and Molecular Biology
IdentifiersURN: urn:nbn:se:uu:diva-246862DOI: 10.1126/scisignal.aaa4636ISI: 000347920200001OAI: oai:DiVA.org:uu-246862DiVA: diva2:794512