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Pseudoexfoliation and mortality: a population-based 30-year follow-up study
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Neuroscience, Ophthalmology.
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Neuroscience, Ophthalmology.
2015 (English)In: Acta Ophthalmologica, ISSN 1755-375X, E-ISSN 1755-3768, Vol. 93, no 2, 162-164 p.Article in journal (Refereed) Published
Abstract [en]

PurposeTo study the relationship between pseudoexfoliation (PEX) and all-cause mortality in a population in which PEX is a common finding. MethodsSurvival analyses were performed in a cohort of 760 residents 65-74years of age, examined in a population survey in the municipality of Tierp, Sweden, 1984-86. To expand the cohort, participants in other studies in Tierp were enrolled. Additionally, people were recruited by means of glaucoma case records established at the Eye Department in Tierp in 1978-2007. In this way, the cohort comprised 1524 subjects, representing more than 21100 person-years at risk. Information on deaths was obtained from the local population register. ResultsBy the conclusion of the study, in August 2013, 1280 deaths had been reported. Of these cases, 350 were affected by PEX at baseline. No association between PEX and mortality was found (hazard ratio 1.00; 95% confidence interval 0.88-1.14). ConclusionThe results strongly suggest that PEX had no effect on all-cause mortality in the population under study.

Place, publisher, year, edition, pages
2015. Vol. 93, no 2, 162-164 p.
Keyword [en]
all-cause mortality, epidemiology, exfoliation syndrome, mortality rate, pseudoexfoliation, risk factor, survival
National Category
Ophthalmology
Identifiers
URN: urn:nbn:se:uu:diva-248428DOI: 10.1111/aos.12402ISI: 000349900200034PubMedID: 24674619OAI: oai:DiVA.org:uu-248428DiVA: diva2:801883
Available from: 2015-04-10 Created: 2015-03-30 Last updated: 2017-12-04Bibliographically approved

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