A simple track structure model of ion beam radiotherapy.
2006 (English)In: Radiation Protection Dosimetry, ISSN 0144-8420, E-ISSN 1742-3406, Vol. 122, no 1-4, 471-4 p.Article in journal (Refereed) Published
A simple radiotherapy ion beam calculation based on the cellular track structure model, using in vitro cell survival parameters fitted from recent experimental data, is presented. The calculation represents a single-fraction ion exposure (roughly corresponding to a 2 Gy fraction of megavolt X rays) and exploits concepts used in clinical radiotherapy, such as entrance, or 'skin' ion dose. The depth distribution of cells surviving their irradiation by a beam of 385 MeV amu(-1) carbon ions is calculated over the range of the stopping ions, as a sequence of track-segments, in the continuous slowing-down approximation. An interpretation of the 'clinical relative biological effectiveness' concept is suggested.
Place, publisher, year, edition, pages
2006. Vol. 122, no 1-4, 471-4 p.
Other Medical Engineering Other Physics Topics
IdentifiersURN: urn:nbn:se:uu:diva-249152DOI: 10.1093/rpd/ncl471PubMedID: 17127682OAI: oai:DiVA.org:uu-249152DiVA: diva2:802157