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Treatment modality affects long-term quality of life in gynaecological cancer.
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Public Health and Caring Sciences. (Nursing School)
2000 (English)In: Anticancer Research, ISSN 0250-7005, Vol. 20, no 1B, 563-568 p.Article in journal (Refereed) Published
Abstract [en]

In order to survey the side effects after cancer treatment, quality of life data were collected from females in clinical remission.


The study was cross-sectional; every patient that visited the outpatient clinic during a period of three months was asked to anonymously complete the EORTC QLQ-C30 questionnaire and five additional specific questions related to gynaecological cancer.


In total, 235 patients (90%) returned the questionnaire. In general, both the levels of functioning and symptomatology were time-dependent. Patients with short treatment-free intervals reported more problems than the others. When using treatment modality as an independent variable in the statistical calculations, a treatment-related effect on functioning and symptomatology was demonstrated (p < 0.05 to p < 0.001). Patients previously treated with chemotherapy had poorer role- and cognitive functioning and more problems with fatigue, nausea, vomiting, dyspnoea, constipation and financial problems, compared with those not treated with chemotherapy (p < 0.05 to p < 0.01). Those patients who had been treated with external radiotherapy and/or brachytherapy had significantly more problems with flatulence and diarrhoea (p < 0.05 to p < 0.001). In conclusion, patients who underwent treatment for gynaecological cancer reported long-term side effects also many years after finishing treatment. The problems where related to treatment modality which should be considered, especially when planning adjuvant treatment.

Place, publisher, year, edition, pages
The International Institute of Anticancer Research , 2000. Vol. 20, no 1B, 563-568 p.
Keyword [en]
Gynaecological cancer, clinical omission, quality of life, side effects
National Category
Nursing Obstetrics, Gynecology and Reproductive Medicine Cancer and Oncology
URN: urn:nbn:se:uu:diva-53232ISI: 000086326600018PubMedID: 10769726OAI: oai:DiVA.org:uu-53232DiVA: diva2:81142
Available from: 2008-10-17 Created: 2008-10-17 Last updated: 2011-08-19Bibliographically approved

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