uu.seUppsala University Publications
Change search
ReferencesLink to record
Permanent link

Direct link
Overall mortality among patients surviving an episode of peptic ulcer bleeding
Show others and affiliations
2000 (English)In: Journal of Epidemiology and Community Health, ISSN 0143-005X, E-ISSN 1470-2738, Vol. 54, 130-133 p.Article in journal (Refereed) Published
Abstract [en]

STUDY OBJECTIVE: The authors investigated whether patients who have survived an acute episode of peptic ulcer bleeding (PUB) have an excess long term all cause mortality compared with the general population free of PUB.

DESIGN: Follow up study of previously identified cohort of patients with a PUB episode and a general population cohort.

SETTING: The source population included all people aged 30 to 89 years, registered with general practitioners in the United Kingdom.

PATIENTS: All patients alive one month after the PUB episode constituted the cohort of PUB patients (n = 978). A control group of 5000 people was randomly sampled from the source population. The same eligibility criteria as for patients with PUB were applied to the control series. Also, controls had to be free of PUB before start date.

MAIN RESULTS: Relative risk of mortality among PUB patients was 2.1, 95% CI: 1.7, 2.6) compared with the general population. This increased mortality risk occurred mainly in the patients less than 60 years old. No difference was observed between men and women. The excess mortality was not only circumscribed to deaths attributable to recurrent gastrointestinal bleed, but also cardiovascular, cancer and other causes.

CONCLUSIONS: People who have survived an acute episode of PUB have a reduced long term survival compared with the general population. This reduction was stronger among middle age patients than in the elderly.

Place, publisher, year, edition, pages
2000. Vol. 54, 130-133 p.
National Category
Medical and Health Sciences
URN: urn:nbn:se:uu:diva-53407DOI: 10.1136/jech.54.2.130PubMedID: 10715746OAI: oai:DiVA.org:uu-53407DiVA: diva2:81317
Available from: 2008-10-17 Created: 2008-10-17 Last updated: 2013-11-07Bibliographically approved

Open Access in DiVA

No full text

Other links

Publisher's full textPubMed

Search in DiVA

By author/editor
Wallander, Mari-Ann
By organisation
Family Medicine and Clinical Epidemiology
In the same journal
Journal of Epidemiology and Community Health
Medical and Health Sciences

Search outside of DiVA

GoogleGoogle Scholar
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

Altmetric score

Total: 152 hits
ReferencesLink to record
Permanent link

Direct link