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Evaluation of the Alere NT-proBNP Test for Point of Care Testing
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences, Biochemial structure and function.
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences, Biochemial structure and function.
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences, Biochemial structure and function.
2016 (English)In: Journal of clinical laboratory analysis (Print), ISSN 0887-8013, E-ISSN 1098-2825, Vol. 30, no 4, p. 290-292Article in journal (Refereed) Published
Abstract [en]

BACKGROUND: The object of the study was to evaluate the Alere point of care NT-proBNP assay as a suitable alternative to the central laboratory method to provide short test turnaround times in primary care.

METHOD: Blood NT-proBNP results obtained with the Alere assay (n = 100) were compared with serum NT-proBNP results analyzed by a Cobas 8000 analyzer (Roche Diagnostics, Mannheim, Germany).

RESULTS: There was a good agreement between the two NT-proBNP methods when used as a rule-out test for heart failure (HF) and the cut-off value <300 ng/l. A total of 47 samples gave values <300 ng/L with both methods and 51 samples gave values >300 with both methods. Thus, there was an agreement for 98% of the samples.

CONCLUSIONS: The study shows that the Alere NT-proBNP assay could be used in primary care permitting rapid NT-proBNP testing to rule out HF.

Place, publisher, year, edition, pages
2016. Vol. 30, no 4, p. 290-292
National Category
Cardiac and Cardiovascular Systems
Identifiers
URN: urn:nbn:se:uu:diva-253175DOI: 10.1002/jcla.21853ISI: 000380030800003PubMedID: 25950992OAI: oai:DiVA.org:uu-253175DiVA, id: diva2:813587
Available from: 2015-05-23 Created: 2015-05-23 Last updated: 2017-12-04Bibliographically approved

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Carlsson, LenaLarsson, Anders

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