Evaluation of the Alere NT-proBNP Test for Point of Care Testing
2016 (English)In: Journal of clinical laboratory analysis (Print), ISSN 0887-8013, E-ISSN 1098-2825, Vol. 30, no 4, 290-292 p.Article in journal (Refereed) Published
BACKGROUND: The object of the study was to evaluate the Alere point of care NT-proBNP assay as a suitable alternative to the central laboratory method to provide short test turnaround times in primary care.
METHOD: Blood NT-proBNP results obtained with the Alere assay (n = 100) were compared with serum NT-proBNP results analyzed by a Cobas 8000 analyzer (Roche Diagnostics, Mannheim, Germany).
RESULTS: There was a good agreement between the two NT-proBNP methods when used as a rule-out test for heart failure (HF) and the cut-off value <300 ng/l. A total of 47 samples gave values <300 ng/L with both methods and 51 samples gave values >300 with both methods. Thus, there was an agreement for 98% of the samples.
CONCLUSIONS: The study shows that the Alere NT-proBNP assay could be used in primary care permitting rapid NT-proBNP testing to rule out HF.
Place, publisher, year, edition, pages
2016. Vol. 30, no 4, 290-292 p.
Cardiac and Cardiovascular Systems
IdentifiersURN: urn:nbn:se:uu:diva-253175DOI: 10.1002/jcla.21853ISI: 000380030800003PubMedID: 25950992OAI: oai:DiVA.org:uu-253175DiVA: diva2:813587