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Serum relaxin, symphyseal pain, and back pain during pregnancy
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Public Health and Caring Sciences, Family Medicine and Clinical Epidemiology.
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Public Health and Caring Sciences, Family Medicine and Clinical Epidemiology.
1996 (English)In: American Journal of Obstetrics and Gynecology, ISSN 0002-9378, E-ISSN 1097-6868, Vol. 175, no 5, 1342-1347 p.Article in journal (Refereed) Published
Abstract [en]

OBJECTIVE

 Our purpose was to study the relationship between serum relaxin levels and back pain during pregnancy.

STUDY DESIGN

 A prospective clinical cohort study with repeated examinations was performed.

RESULTS

There was an initial increase of relaxin levels until a peak value at the twelfth week followed by a decline until the seventeenth week. Thereafter stable serum levels around 50% of the peak value were recorded. Three months after delivery serum relaxin was not detectable. There was a significant correlation between mean serum relaxin levels during the pregnancy and symphyseal pain or low back pain occurring during late pregnancy as measured by medical history or pain-provoking test.

CONCLUSION

 Relaxin is known to remodel pelvic connective tissue in several mammalian species during pregnancy. The current data suggest that relaxin might be involved in the development of pelvic pain in pregnant women.

Place, publisher, year, edition, pages
1996. Vol. 175, no 5, 1342-1347 p.
Keyword [en]
Relaxin, pregnancy, back pain, epidemiology
National Category
Medical and Health Sciences
Identifiers
URN: urn:nbn:se:uu:diva-53622DOI: 10.1016/S0002-9378(96)70052-2PubMedID: 8942512OAI: oai:DiVA.org:uu-53622DiVA: diva2:81532
Available from: 2008-10-17 Created: 2008-10-17 Last updated: 2017-12-04Bibliographically approved

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Kristiansson, PerSvärdsudd, Kurt

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