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Trombolys förändrar vården vid slaganfall
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences.
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1998 (Swedish)In: Läkartidningen, ISSN 0023-7205, Vol. 95, no 28-29, 3202-3211 p.Article in journal (Other academic) Published
Abstract [en]

Thrombolysis using tissue plasminogen activator (tPA) is not the leading strategy in the development of pharmacological treatments for acute ischaemic stroke. The prospect of tPA becoming routine treatment in ischaemic stroke raises several issues the magnitude of the treatment load, the requisite neurological and neuroradiological diagnostic qualifications, identification of local reperfusion effects in the brain, and the pre-hospital and hospital management of acute stroke patients. The results of large randomised trials of intravenous tPA treatment are reviewed in the article, and the current state of our knowledge about interventional thrombolysis is reported. Recruitment for the second European intravenous tPA trail, ECASS II, has recently been completed, and the study findings will be available during the latter half of 1988. In the USA, tPA is already recommended treatment for acute ischaemic stroke within three hours after the onset of symptoms. In Europe, the formulation of guidelines awaits the results of ECASS II.

Place, publisher, year, edition, pages
1998. Vol. 95, no 28-29, 3202-3211 p.
National Category
Medical and Health Sciences
URN: urn:nbn:se:uu:diva-54300PubMedID: 9700267OAI: oai:DiVA.org:uu-54300DiVA: diva2:82209
Available from: 2008-10-17 Created: 2008-10-17 Last updated: 2010-12-09Bibliographically approved

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