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Sex ratio of multiple sclerosis in the National Swedish MS Register (SMSreg)
Department of Clinical and Experimental Medicine, Division of Neuroscience, Linköping University, Sweden.
2013 (English)In: Multiple Sclerosis, ISSN 1352-4585, E-ISSN 1477-0970, Vol. 19, no 1, 46-52 p.Article in journal (Refereed) Published
Abstract [en]

BACKGROUND: Sex ratio in multiple sclerosis has been reported from several geographical areas. The disease is more common in women. In Europe the female-to-male ratio varies from 1.1 to 3.4. A recent study from Canada has reported a significant increase, with time, in female-to-male ratio in multiple sclerosis over the last 100 years.

OBJECTIVE: The aim of this study was to analyse any change in sex ratio in multiple sclerosis in the Swedish population.

METHODS: Data from the Swedish MS Register and data from the Swedish National Statistics Office were used to estimate sex ratio by year of birth and year of onset.

RESULTS: In the analysis of sex ratio by year of birth there were 8834 patients (6271 women and 2563 men) born between 1931 and 1985. The mean women-to-men ratio was 2.62. No clear trend was noted for the women-to-men ratio by year of birth (Spearman's rho = 0.345, p = 0.298, n = 11). The number of patients analysed by year of onset was 9098 during the time period 1946 until 2005. The mean women-to-men ratio was 2.57. No significant change in women-to-men ratio (Spearman's rho = -0.007, p = 0.983, n = 12) with time was observed.

CONCLUSION: There is no evidence for an increasing women-to-men ratio with time amongst Swedish multiple sclerosis patients.

Place, publisher, year, edition, pages
2013. Vol. 19, no 1, 46-52 p.
National Category
URN: urn:nbn:se:uu:diva-256046DOI: 10.1177/1352458512446169PubMedID: 22711712OAI: oai:DiVA.org:uu-256046DiVA: diva2:824402
Available from: 2015-06-22 Created: 2015-06-22 Last updated: 2015-09-17Bibliographically approved

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Landtblom, Anne-Marie
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