uu.seUppsala University Publications
Change search
ReferencesLink to record
Permanent link

Direct link
Hydrogen bond diversity in the pre-polymerization stage contributes to morphology and MIP-template recognition - MAA versus MMA
Show others and affiliations
2015 (English)In: European Polymer Journal, ISSN 0014-3057, E-ISSN 1873-1945, Vol. 66, 558-568 p.Article in journal (Refereed) Published
Abstract [en]

This report demonstrates that the diversity of hydrogen bond interactions present in molecularly imprinted polymer pre-polymerization mixtures, typically associated with binding-site heterogeneity, can also contribute to morphological characteristics that may influence polymer-template recognition. Comparisons have been made between a series of bupivacaine molecularly imprinted methacrylic acid (MAA)-ethylene glycol dimethacrylate (EGDMA) copolymers and a series of analogous methyl methacrylate (MMA)-EGDMA copolymers using comprehensive molecular dynamics studies of the respective pre-polymerization mixtures, template-polymer binding studies and detailed BET surface area and BJH porosity analyses. The role of the carboxylic acid functionality of MAA, and in particular the acidic proton, in generating morphological features conducive to analyte access (slit-like rather than ink bottle-like structures) and recognition is discussed.

Place, publisher, year, edition, pages
2015. Vol. 66, 558-568 p.
Keyword [en]
Molecularly imprinted polymer, Molecular dynamics, Molecular recognition, Molecular imprinting, Morphology
National Category
Polymer Chemistry
URN: urn:nbn:se:uu:diva-253236DOI: 10.1016/j.eurpolymj.2015.03.018ISI: 000353854000057OAI: oai:DiVA.org:uu-253236DiVA: diva2:824553
Available from: 2015-06-22 Created: 2015-05-25 Last updated: 2015-06-22Bibliographically approved

Open Access in DiVA

No full text

Other links

Publisher's full text
By organisation
Department of Chemistry - BMC
In the same journal
European Polymer Journal
Polymer Chemistry

Search outside of DiVA

GoogleGoogle Scholar
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

Altmetric score

Total: 113 hits
ReferencesLink to record
Permanent link

Direct link