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Synthesis and anticancer properties of fucoidan-mimetic glycopolymer coated gold nanoparticles
Uppsala University, Disciplinary Domain of Science and Technology, Chemistry, Department of Chemistry - Ångström, Polymer Chemistry.
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2015 (English)In: Chemical Communications, ISSN 1359-7345, E-ISSN 1364-548X, Vol. 51, no 40, 8532-8535 p.Article in journal (Refereed) Published
Abstract [en]

Gold nanoparticles coated with fucoidan-mimetic glycopolymers were synthesized that displayed good colloidal stability and promising anti-cancer properties. Fucoidan mimetic glycopolymers on their own were nontoxic, while glycopolymer coated gold nanoparticles displayed selective cytotoxicity to human colon cancer cell lines (HCT116) while it was non-toxic to mouse fibroblast cells (NIH3T3).

Place, publisher, year, edition, pages
2015. Vol. 51, no 40, 8532-8535 p.
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Chemical Sciences
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URN: urn:nbn:se:uu:diva-256558DOI: 10.1039/c5cc02387dISI: 000354043200034PubMedID: 25892661OAI: oai:DiVA.org:uu-256558DiVA: diva2:825986
Available from: 2015-06-24 Created: 2015-06-24 Last updated: 2017-12-04Bibliographically approved

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Oommen, Oommen Podiyan

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