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(Lipo)polysaccharide interactions of antimicrobial peptides
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Pharmacy, Department of Pharmacy.
2015 (English)In: Journal of Colloid and Interface Science, ISSN 0021-9797, E-ISSN 1095-7103, Vol. 449, 136-142 p.Article in journal (Refereed) Published
Abstract [en]

Due to rapidly increasing resistance development against conventional antibiotics, as well as problems associated with diseases either triggered or deteriorated by infection, antimicrobial and anti-inflammatory peptides have attracted considerable interest during the last few years. While there is an emerging understanding of the direct antimicrobial function of such peptides through bacterial membrane destabilization, the mechanisms of their anti-inflammatory function are less clear. We here summarize some recent results obtained from our own research on anti-inflammatory peptides, with focus on peptide(lipo)polysaccharide interactions. (C) 2014 Elsevier Inc. All rights reserved.

Place, publisher, year, edition, pages
2015. Vol. 449, 136-142 p.
Keyword [en]
Anti-inflammatory, Antimicrobial, Lipid A, Lipopolysaccharide, Peptide
National Category
Pharmacology and Toxicology
Identifiers
URN: urn:nbn:se:uu:diva-255036DOI: 10.1016/j.jcis.2014.11.024ISI: 000353848300017PubMedID: 25490856OAI: oai:DiVA.org:uu-255036DiVA: diva2:826155
Available from: 2015-06-24 Created: 2015-06-12 Last updated: 2017-12-04Bibliographically approved

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Malmsten, Martin

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