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Läkemedelsgenomgångar av apotekare inom slutenvårdspsykiatrin i Kalmar - typ av läkemedelsrelaterade problem samt åtgärdsfrekvens
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Pharmacy, Department of Pharmaceutical Biosciences.
2015 (Swedish)Independent thesis Advanced level (degree of Master (One Year)), 10 credits / 15 HE creditsStudent thesis
Abstract [en]

Title: Medication reviews by a clinical pharmacist in psychiatric wards in Kalmar - type of drug-related problems and implementation rate of recommended interventions

Author: Fredriksson E. Supervisor: Hedebäck F. and Hellström L. Examiner: Nielsen E. Institute: Uppsala University, Uppsala, Sweden.

Background and Objective: Drug-related problems (DRPs) are common and medication reviews can reduce their frequency. Few studies have evaluated medication reviews by pharmacists in psychiatry. The objective of this study is to describe type of DRPs identified through medication reviews conducted by a pharmacist, recommendations made by the pharmacist during ward rounds and/or in the medical record and implementation rate of recommended interventions in adult inpatient psychiatry in Kalmar. Also to describe drug types involved in DRPs and precipitating factors that some patients receive a detailed medication review.

Design: Observational, prospective study. A clinical pharmacist identified DRPs through medication reviews in three psychiatric wards. The pharmacist participated on ward rounds making recommendations for solutions of identified problems and/or documenting recommended interventions in the medical record. Type of DRPs, type of and implemented interventions and drugs involved in DRPs were analysed with descriptive statistics.

Setting: The study was conducted at Kalmar hospital between February 2nd and April 2nd 2015.

Main outcome measures: Type of DRPs, recommendations made by the pharmacist and rate of implementation of recommended interventions.

Results: The study included 50 patients with median (interquartile range) 2 (1-4) DRPs per patient. The most common DRP was no valid indication (25 %). Most common intervention was discontinuing drug therapy (46 %). Implementation rate was 74 %, including doctor’s implementation of recommendations and problems resolved by the pharmacist during patient conversation. Drugs involved in DRPs were primarily drugs affecting the nervous system, mainly antipsychotics. The precipitating factor for more detailed reviews was request from psychiatrists.

Conclusion: This study implies that medication reviews by a clinical pharmacist participating in psychiatric ward rounds can help identify and resolve DRPs, with high implementation rate of recommended interventions. Antipsychotics is the medication type most often involved in DRPs. Further studies are needed to assess the clinical benefit of medication reviews by pharmacists in psychiatry.

Place, publisher, year, edition, pages
2015. , 15 p.
Keyword [en]
clinical pharmacy, psychiatry
Keyword [sv]
klinisk farmaci, psykiatri
National Category
Social and Clinical Pharmacy
URN: urn:nbn:se:uu:diva-256941OAI: oai:DiVA.org:uu-256941DiVA: diva2:827760
External cooperation
Landstinget i Kalmar län
Subject / course
Available from: 2015-06-29 Created: 2015-06-29 Last updated: 2015-06-29Bibliographically approved

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