uu.seUppsala University Publications
Change search
ReferencesLink to record
Permanent link

Direct link
Confirmation of nosocomial transmission of hepatitis C virus by phylogenetic analysis of the NS5-B region
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences. (Friman, infektion)
Show others and affiliations
1998 (English)In: Journal of Clinical Microbiology, ISSN 0095-1137, E-ISSN 1098-660X, Vol. 36, no 10, 3066-3069 p.Article in journal (Refereed) Published
Abstract [en]

Four hepatitis C virus transmission chains at three dialysis units were disclosed by limited sequencing; three of these were disclosed by analysis of the NS5-B region of the genome. Dialysis on the same shift as that during which infected patients were dialyzed was the common factor for seven patients in two chains. Two nurses exposed to needle sticks and their sources of infection constituted two other chains. The strains of three chains belonged to subtype 1a and formed clusters with an intrachain variability of 0 to 6 nucleotides compared to 8 to 37 nucleotides for unrelated strains within this subtype. The clusters were supported by bootstrap values ranging from 89 to 100%.

Place, publisher, year, edition, pages
1998. Vol. 36, no 10, 3066-3069 p.
National Category
Medical and Health Sciences
URN: urn:nbn:se:uu:diva-55455PubMedID: 9738071OAI: oai:DiVA.org:uu-55455DiVA: diva2:83363
Available from: 2008-10-17 Created: 2008-10-17 Last updated: 2010-10-06Bibliographically approved

Open Access in DiVA

No full text

By organisation
Department of Medical Sciences
In the same journal
Journal of Clinical Microbiology
Medical and Health Sciences

Search outside of DiVA

GoogleGoogle Scholar
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

Altmetric score

Total: 170 hits
ReferencesLink to record
Permanent link

Direct link