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The potential clinical impact of the tissue-based map of the human proteome
Uppsala University, Science for Life Laboratory, SciLifeLab. Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Immunology, Genetics and Pathology.
2015 (English)In: Expert Review of Proteomics, ISSN 1478-9450, E-ISSN 1744-8387, Vol. 12, no 3, 213-215 p.Article in journal, Editorial material (Other academic) Published
Abstract [en]

Since the first draft of the human genome sequence was published, several attempts have been made to map the human proteome, the functional representation of the genome. One such initiative is the Human Protein Atlas project, which recently released a tissue-based map of the human proteome. The Human Protein Atlas is based on the combination of transcriptomics and antibody-based proteomics for mapping the human proteome down to the single cell level. The comprehensive publicly available database contains more than 13 million unique immunohistochemistry images and provides an excellent resource for exploration and investigation of future drug targets and disease biomarkers.

Place, publisher, year, edition, pages
2015. Vol. 12, no 3, 213-215 p.
Keyword [en]
immunohistochemistry, proteome, proteomics, tissue microarrays, transcriptomics
National Category
Other Basic Medicine
URN: urn:nbn:se:uu:diva-257333DOI: 10.1586/14789450.2015.1040771ISI: 000354610000001PubMedID: 25925092OAI: oai:DiVA.org:uu-257333DiVA: diva2:839002
Available from: 2015-07-01 Created: 2015-07-01 Last updated: 2015-11-06Bibliographically approved

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Lindskog, Cecilia
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Science for Life Laboratory, SciLifeLabDepartment of Immunology, Genetics and Pathology
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