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Mathematical modeling of normal and cancer prostate signaling pathways
Uppsala University, Disciplinary Domain of Science and Technology, Biology, Biology Education Centre. Thomas Helleday group, KI / Science for Life Laboratory, Stockholm.
2015 (English)Independent thesis Advanced level (degree of Master (Two Years)), 30 credits / 45 HE creditsStudent thesis
Abstract [en]

The field of systems biology has become very popular as a means to deal with cancer as well as other complex biological issues. It enables scientists to gain an insight into difficult conditions through mathematical approaches that have been developed. Prostate cancer is the second leading cause of death among men after skin cancer and its heterogeneity makes it a complex disease. In this study we focus on three pathways known to play crucial roles in the formation of prostate cancer. By using a mathematical model that combines all of them we describe the interactions taking place during signal transduction in the prostate under normal and cancer conditions. 

Place, publisher, year, edition, pages
2015. , 38 p.
Keyword [en]
prostate cancer, MAPK pathway, prostate cancer signaling
National Category
Bioinformatics (Computational Biology)
Identifiers
URN: urn:nbn:se:uu:diva-257431OAI: oai:DiVA.org:uu-257431DiVA: diva2:839298
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Available from: 2015-07-02 Created: 2015-07-02 Last updated: 2015-07-04Bibliographically approved

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