Association between the maternal iron status (ferritin level) during pregnancy and infant birth weight: A secondary analysis of data from the MINIMat trial in Matlab, Bangladesh
Independent thesis Advanced level (degree of Master (Two Years)), 20 credits / 30 HE creditsStudent thesis
Low birth weight is a crucial public health issue as it is one underlying cause of child mortality, morbidity and health impairment later in life. Maternal nutritional status is associated with birth weight, and maternal nutrition is in turn related to the common nutritional disorder iron deficiency.
Aim: To investigate the association between maternal iron status (ferritin level) at gestational week 14 and 30 during pregnancy and infant birth weight.
Methods: The randomized MINIMat(Maternal and Infant Nutrition Interventions, Matlab)-trial in Bangladesh was carried out from 2001-2003 with follow-ups until 2009. On selected data from the MINIMat-trial a secondary analysis was conducted in this study, with a subsample of 576 women.
Results: Univariate linear regression with maternal ferritin levels (measured at gestational week 14 and 30) and infant birth weight showed no significant association. Multiple linear regression, adjusted for maternal anthropometric- and socio-demographic characteristics as well as gestational age at birth, showed a significant negative association between maternal ferritin level and infant birth weight (parameter estimate -1.46, CI: -2.47 to -0.45, for ferritin level at week 14 of gestation, and -2.61, CI: -4.70 to -0.52, for ferritin level at week 30 of gestation).
Conclusion: A higher maternal ferritin level at week 14 and 30 of gestation during pregnancy slightly decreases infant birth weight. Since maternal ferritin level during pregnancy seems to have a small impact on infant birth weight, other factors can be more prioritized as determinants and indicators for infant birth weight to tackle the issue of low birth weight.
Place, publisher, year, edition, pages
2015. , 40 p.
Maternal health, iron deficiency, maternal iron status, ferritin, Bangladesh, birth weight
Public Health, Global Health, Social Medicine and Epidemiology
IdentifiersURN: urn:nbn:se:uu:diva-258403OAI: oai:DiVA.org:uu-258403DiVA: diva2:841524
Master Programme in International Health