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Evaluation of the Meritas® BNP Test for Point-of-Care Testing
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences, Biochemial structure and function.
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences, Biochemial structure and function.
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences, Biochemial structure and function.
2015 (English)In: Clinical Laboratory, ISSN 1433-6510, Vol. 61, no 7, 727-730 p.Article in journal (Refereed) Published
Abstract [en]

Background: BNP and NT-proBNP are widely used as rule-out tests for heart failure (HF) and they are frequently requested by primary care doctors. A point-of-care (POC) test would reduce the time to diagnosis for patients with suspected HF. The aim of the study was to evaluate a POC BNP test.

Methods: Plasma BNP results obtained with the Meritas® POC instrument (n = 82) were compared with the corresponding plasma BNP results analyzed on an Advia Centaur analyzer (Siemens Healthcare, Erlangen, Germany).

Results: The two methods showed concordant results with a Passing-Bablok correlation between the two methods: BNPMeritas = 1.00 x BNPSiemens + 1.09; r = 0.9773.

Conclusions: The study show that the Meritas® BNP assay could be used in primary care permitting rapid BNP testing to rule out heart failure.

Place, publisher, year, edition, pages
2015. Vol. 61, no 7, 727-730 p.
National Category
Clinical Laboratory Medicine
Identifiers
URN: urn:nbn:se:uu:diva-259351DOI: 10.7754/Clin.Lab.2014.140815ISI: 000358180700010OAI: oai:DiVA.org:uu-259351DiVA: diva2:843862
Available from: 2015-07-31 Created: 2015-07-31 Last updated: 2017-12-04Bibliographically approved

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Petterson, ChristerLarsson, Anders

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