uu.seUppsala University Publications
Change search
ReferencesLink to record
Permanent link

Direct link
Can Cobalt(II) and Chromium(III) Ions Released from Joint Prostheses Influence the Friction Coefficient?
Uppsala University, Disciplinary Domain of Science and Technology, Technology, Department of Engineering Sciences, Applied Materials Sciences. (Materials in Medicin)
Show others and affiliations
2015 (English)In: ACS Biomaterials Science & Engineering, Vol. 1, no 8, 617-620 p.Article in journal (Refereed) Published
Abstract [en]

Cobalt chromium molybdenum alloys (CoCr-Mo) are commonly used as articulating components in joint prostheses. In this tribocorrosive environment, wear debris and metal ionic species are released and interact with proteins, possibly resulting in protein aggregation. This study aimed to investigate whether this could have an eff ect on the friction coefficient in a typical material couple, namely CoCrMo-onpolyethylene. It was confirmed that both Co(II) and Cr(III) ions, and their combination, at concentrations relevant for the metal release situation, resulted in protein aggregation and its concomitant precipitation, which increased the friction coeffi cient. Future studies should identify the clinical importance of these findings.

Place, publisher, year, edition, pages
2015. Vol. 1, no 8, 617-620 p.
Keyword [en]
hip joint, replacement, friction, protein-metal binding, CoCrMo, alloy tribology
National Category
Other Materials Engineering Medical Materials
Research subject
Engineering Science with specialization in Materials Science
URN: urn:nbn:se:uu:diva-259426DOI: 10.1021/acsbiomaterials.5b00183ISI: 000372214100001OAI: oai:DiVA.org:uu-259426DiVA: diva2:844097
EU, FP7, Seventh Framework Programme, GA-310477Swedish Research Council, 2013-5621
Available from: 2015-08-03 Created: 2015-08-03 Last updated: 2016-04-14Bibliographically approved

Open Access in DiVA

fulltext(1391 kB)50 downloads
File information
File name FULLTEXT01.pdfFile size 1391 kBChecksum SHA-512
Type fulltextMimetype application/pdf

Other links

Publisher's full text

Search in DiVA

By author/editor
Persson, Cecilia
By organisation
Applied Materials SciencesApplied Materials Sciences
Other Materials EngineeringMedical Materials

Search outside of DiVA

GoogleGoogle Scholar
Total: 50 downloads
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

Altmetric score

Total: 444 hits
ReferencesLink to record
Permanent link

Direct link