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Handläggning av patienter med misstänkt neuroborrelios i Uppsala län
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Pharmacy, Department of Pharmaceutical Biosciences.
2015 (Swedish)Independent thesis Advanced level (degree of Master (Two Years)), 20 credits / 30 HE creditsStudent thesis
Abstract [en]

Introduction:  Lyme borreliosis is an infectious disease, caused by bacteria called Borrelia burgdorferi. The disease is spread to humans by infected ticks and around one sixth develop Lyme neuroborreliosis. It is a condition which is difficult to diagnose. For the correct diagnosis a lumbar puncture needs to be performed. A diagnose based only on the clinical picture and serology could end up in unnecessarily prescribed antibiotics. Excessive use of antibiotics leads to antibiotic resistance which is a growing global threat.

Aim: The aim is to investigate in what extent the national recommendations are being followed when patients are diagnosed with neuroborreliosis and to investigate where within the healthcare the diagnose has been determined. This is of interest since Strama would like to identify which improvement oppurtunities there are for a more effective usage of antibiotics.

Materials and Methods: Data of patients visiting the open care and the inpatient care, being registrated with the diagnosis code; A692, Infection caused by Borrelia Burgdoferi during January – Decemeber 2014 were collected from the country council’s output device. From the the medical records of every patient visting the healthcare, it was possible to identify how patients were being diagnosed and treated in this retrospective study. 

Results: Out of all 84 patients registrated with A692 in the open care, 88% of the patients were handled incorrectly and were prescribed antibiotics. In the inpatient care, 61% of the patients were handled incorrectly. The majority were prescribed antibiotics without lumbar puncture. 

Conclusions: This study shows that the national recommendations are not being followed and that the majority of the patients being treated for Lyme neuroborreliosis  do not go through a lumbar puncture. Being prescribed antibiotics without performing this, can result in an incorrect diagnose and  give rise to increased antibiotic resistance.

Place, publisher, year, edition, pages
2015. , 46 p.
Keyword [en]
Antibiotic resistance, Lyme neuroborreliosis, Strama, Lumbar puncture, Ticks
Keyword [sv]
Antibiotikaresistens, Neuroborrelios, Strama, Lumbalpunktion, Fästingar
National Category
Social and Clinical Pharmacy
URN: urn:nbn:se:uu:diva-259698OAI: oai:DiVA.org:uu-259698DiVA: diva2:845126
External cooperation
Strama Uppsala
Subject / course
Educational program
Master of Science Programme in Pharmacy
Available from: 2015-08-11 Created: 2015-08-10 Last updated: 2015-08-11Bibliographically approved

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